The National Drug Abuse Research Clinical Trials Network (CTN) sponsored a study referenced as CTN-0044.
The Primary Objective of CTN-0044 was to conduct a multi-site trial of the effectiveness Trial of TES as an interactive, web-based version of the Community Reinforcement Approach (CRA) plus incentives targeting drug abstinence and treatment participation as part of community-based, outpatient substance abuse treatment
1. TES effect was greater among patients who tested positive for substances at baseline
2. Findings suggest that TES can be substituted for a portion of face-to-face counseling and produce better outcomes (i.e., abstinence and retention)
Campbell et al (2014)
American Indian population
In outpatients with opioid dependence, computer-administered CRA with vouchers produced similar abstinence weeks & longer continuous abstinence than therapist-administered CRA with vouchers and reduced therapist time. (Bickel et al., 2008)
TES was an effective adjunct to HIV prevention education for youth in substance abuse treatment.
TES plus counseling produced greater 12-month abstinence than counseling alone. (Marsch et al., 2011)
In a prison population, TES was as effective as standard treatment in
Campbell, A.N.C., Nunes, E.V., Matthews, A.G., Stitzer, M., Miele, G.M., Polsky, D., Turrigiano, E., Walters, S., McClure, EA., Kyle, T.L., Wahle, A., van Veldhuisen, P., Goldman, B., Babcock, D., Stabile, P.Q., Winhusen, T., Ghitza, U.E. (2014) Internet-delivered treatment for substance abuse: A multi-site randomized controlled trial. American Journal of Psychiatry. i71:683-690
Campbell, Aimee N. C.; Miele, Gloria M.; Nunes, Edward V.; McCrimmon, Scott; Ghitza, Udi E.Web-based, psychosocial treatment for substance use disorders in community treatment settings.Psychological Services, Vol 9(2), May 2012, 212-214
Marsch, L.A., Guarino, H., Acosta, M., Aponte-Melendez, Y., Cleland, C., Grabinski, M., Brady, r.,Edwards, J. (2014). Web-based behavioral treatment for substance use disorders as a partial replacement of standard methadone maintenance treatment. Journal of Substance Abuse Treatment, 46(1), 43–51.
Bickel, W. K., Marsch, L. A., Buchhalter, A. R., & Badger, G. J. (2008). Computerized behavior therapy for opioid-dependent outpatients: A randomized controlled trial. Experimental and Clinical Psychopharmacology, 16(2), 132–143
Marsch, L. A., Grabinski M. J., Bickel, W. K., Desrosiers, A., Guarino, H., Muehlbach, B., . . . Acosta, M. (2011).Computer-Assisted HIV Prevention for Youth with substance use disorders. Substance Use & Misuse, 46(1), 46-56.